Pain Killers


It is recommended that people on warfarin avoid aspirin or aspirin containing medicines as these can increase the risk of bleeding.
Some people with a history of stroke or heart attack may be put on aspirin and warfarin. This combination should only be taken on the recommendation of a doctor.

Anti inflammatories

Voltaren, Brufen, Naproxen and Nurofen
These medicines can increase the risk of bleeding and alternative painkillers such as paracetamol or codeine should be used instead.


This is safe to use when taking warfarin but very high doses can increase the effect of warfarin but not at standard doses.


This is sometimes combined with other pain killers. Paradex for example contains both dextropropoxphene and paracetamol. Dextropropoxyphene can increase the effect of warfarin and should be used cautiously