Therapeutic Ranges

INR	Clinical state
2.0 – 2.5	DVT prophylaxis
2.0 – 3.0	Treatment of DVT/PE Systemic embolus atrial fibrillation TIAs LV mural thrombus Mitral valve repair
2.5 – 3.5	Tissue heart valves Mechanical prosthetic heart valves implanted after 1990 Recurrent DVT/PE
3.0 – 3.5	DVT/PE with lupus anticoagulant (a lower range may be sufficient) Mechanical prosthetic heart valves implanted before 1990