| INR | Clinical state | 
| 2.0 – 2.5 | DVT prophylaxis | 
| 2.0 – 3.0 | Treatment of DVT/PE Systemic embolus
 atrial fibrillation
 TIAs
 LV mural thrombus
 Mitral valve repair
 | 
| 2.5 – 3.5 | Tissue heart valves Mechanical prosthetic heart valves implanted after 1990
 Recurrent DVT/PE
 | 
| 3.0 – 3.5 | DVT/PE with lupus anticoagulant (a lower range may be sufficient)
 Mechanical prosthetic heart valves implanted before 1990
 |